Table of Contents What Is Rapamycin and How Does It Work? Is Rapamycin Safe for Humans? What the Evidence Says Potential Risks and Side Effects Practical Considerations for Use References and Resources TL;DR: Rapamycin is generally considered safe for humans at low doses under medical supervision, but it carries real risks — including immune suppression…
Table of Contents Does Rapamycin Extend Lifespan? How Rapamycin Works: The mTOR Pathway What the Evidence Shows Risks and Limitations Practical Considerations References and Resources Frequently Asked Questions TL;DR: Rapamycin reliably extends lifespan in mice by inhibiting the mTOR pathway, but strong human evidence is still lacking. It remains a promising but unproven longevity intervention,…
Table of Contents Autophagy and Muscle Growth: The Core Tension How Fasting, mTOR, and AMPK Shape the Balance Strategies to Support Both Processes Practical Considerations: Fasting, Sleep, and Recovery Common Myths and Misconceptions Conclusion Frequently Asked Questions References and Resources TL;DR: Autophagy and muscle growth use opposing biological signals, but they can coexist with smart…
Table of Contents Does a 24-Hour Fast Activate Autophagy? How Fasting Triggers Autophagy: The Key Mechanisms What the Evidence Actually Shows Practical Considerations for a 24-Hour Fast Limitations and Important Nuances References and Resources Frequently Asked Questions Conclusion TL;DR: A 24-hour fast is likely sufficient to meaningfully elevate autophagy in most people, with autophagic activity…
Table of Contents What Is Autophagy and How Does Fasting Trigger It? How Long Do You Need to Fast to Activate Autophagy? What the Evidence Actually Shows Practical Implications for Fasting and Autophagy Limitations and Important Caveats References and Resources TL;DR: Meaningful autophagy activation in humans appears to begin around 16–18 hours into a fast,…
Table of Contents Understanding Autophagy: The Basics Is Autophagy Beneficial? Exploring Its Health Benefits How Does Autophagy Work in the Body? Can Autophagy Be Induced Naturally? Frequently Asked Questions About Autophagy References and Resources Understanding Autophagy: The Basics Autophagy is a fundamental biological process that allows cells to clean out damaged components and recycle them…